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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PTPRB
All Species:
18.79
Human Site:
S1658
Identified Species:
51.67
UniProt:
P23467
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23467
NP_002828.3
1997
224328
S1658
E
R
P
S
A
R
L
S
I
R
R
D
R
P
L
Chimpanzee
Pan troglodytes
XP_509219
1996
223893
S1657
E
R
P
S
A
R
L
S
I
R
R
D
R
P
L
Rhesus Macaque
Macaca mulatta
XP_001117455
1997
224328
S1658
E
R
P
S
A
R
L
S
I
R
R
D
R
P
L
Dog
Lupus familis
XP_538283
2367
264000
S1876
E
R
P
S
A
R
L
S
I
R
R
D
R
P
L
Cat
Felis silvestris
Mouse
Mus musculus
Q64455
1238
136750
K918
F
S
Q
I
K
P
K
K
S
K
L
I
R
V
E
Rat
Rattus norvegicus
Q64612
1711
187274
M1392
L
R
L
H
R
P
L
M
I
Q
T
L
S
Q
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512269
2148
240953
S1809
E
R
P
S
A
R
L
S
I
R
R
D
R
P
L
Chicken
Gallus gallus
Q9W6V5
1406
154195
S1087
S
P
I
K
I
K
K
S
K
M
I
K
V
E
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P35992
1631
185062
R1312
I
L
P
Y
D
H
S
R
F
K
L
Q
P
V
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
97.1
97
75.3
N.A.
24.8
20.6
N.A.
71.5
24.5
N.A.
N.A.
N.A.
25.9
N.A.
N.A.
N.A.
Protein Similarity:
100
97.8
98.4
79.8
N.A.
38.1
37.4
N.A.
81.4
40.5
N.A.
N.A.
N.A.
43.5
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
6.6
20
N.A.
100
6.6
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
13.3
26.6
N.A.
100
13.3
N.A.
N.A.
N.A.
13.3
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
56
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
12
0
0
0
0
0
0
56
0
0
12
% D
% Glu:
56
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% E
% Phe:
12
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
12
0
12
0
0
0
0
0
0
0
0
0
% H
% Ile:
12
0
12
12
12
0
0
0
67
0
12
12
0
0
0
% I
% Lys:
0
0
0
12
12
12
23
12
12
23
0
12
0
0
0
% K
% Leu:
12
12
12
0
0
0
67
0
0
0
23
12
0
0
56
% L
% Met:
0
0
0
0
0
0
0
12
0
12
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% N
% Pro:
0
12
67
0
0
23
0
0
0
0
0
0
12
56
0
% P
% Gln:
0
0
12
0
0
0
0
0
0
12
0
12
0
12
0
% Q
% Arg:
0
67
0
0
12
56
0
12
0
56
56
0
67
0
0
% R
% Ser:
12
12
0
56
0
0
12
67
12
0
0
0
12
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
12
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
0
12
23
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
12
0
0
0
0
0
0
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _